Anti-UGT1A1 Antibody

Rabbit polyclonal antibody

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筛选器： All WB IHC ELISA

A01865-1

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Figure 1. Western blot analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1). Lane 1: rat liver tissue lysates,Lane 2: rat kidney tissue lysates,Lane 3: mouse liver tissue lysates,Lane 4: mouse kidney tissue lysates. anti-UGT1A1 antigen affinity purified polyclonal antibody (Catalog # A01865-1)probed with a goat anti-rabbit IgG-HRP secondary antibody The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) . A specific band was detected for UGT1A1 at approximately 59KD. The expected band size for UGT1A1 is at 59KD.
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Figure 2. IHC analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1).UGT1A1 was detected in paraffin-embedded section of rat small intestine tissue. anti-UGT1A1 Antibody (A01865-1) . Biotinylated goat anti-rabbit IgG was used as secondary antibody . The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
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Figure 3. IHC analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1).UGT1A1 was detected in paraffin-embedded section of human rectal cancer tissue. anti-UGT1A1 Antibody (A01865-1) . Biotinylated goat anti-rabbit IgG was used as secondary antibody . The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
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Figure 4. IHC analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1).UGT1A1 was detected in paraffin-embedded section of mouse small intestine tissue. anti-UGT1A1 Antibody (A01865-1) . Biotinylated goat anti-rabbit IgG was used as secondary antibody . The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
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Figure 5. IHC analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1).UGT1A1 was detected in paraffin-embedded section of human mammary cancer tissue. anti-UGT1A1 Antibody (A01865-1) . Biotinylated goat anti-rabbit IgG was used as secondary antibody . The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
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产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-UGT1A1 Antibody

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

GNT1; HUG BR1; UDPGT; UDPGT 1 1; UGT 1A; UGT1; UGT1 01; UGT1*1; UGT1.1; UGT1A; UGT1A1

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

WB,IHC,ELISA

基因名称

UGT1A1

宿主

Rabbit

抗体亚型

IgG

免疫原

E. coli-derived human UGT1A1 recombinant protein (Position: E316-H533).

计算分子量

60 kDa

实际分子量

59 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

Uniprot ID

P22309

文献引用格式

UGT1A1 Antibody (Boster Biological Technology, Wuhan, China. Catalog#A01865-1)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

实验方案>

实验步骤

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