Anti-PTPN6 Antibody (Clone#CGH-16)

Rabbit monoclonal antibody

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筛选器： All WB IHC

BM4236

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of anti-PTPN6 antibody (BM4236). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human Jurkat whole cell lysates,
Lane 2: human Raji whole cell lysates,
Lane 3: human Hela whole cell lysates,
Lane 4: human HepG2 whole cell lysates,
Lane 5: rat liver tissue lysates,
Lane 6: rat RH-35 whole cell lysates,
Lane 7: mouse liver tissue lysates,
Lane 8: mouse Hepa1-6 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-PTPN6 antigen affinity purified monoclonal antibody (BM4236) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for PTPN6 at approximately 68 kDa. The expected band size for PTPN6 is at 68 kDa.
all(2)
Immunohistochemical analysis of paraffin-embedded rat spleen, using SHP1 Antibody.
all(2)

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产品简介>

产品名称

Anti-PTPN6 Antibody (Clone#CGH-16)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

HCP; HCPH; HPTP1C; PTP 1C; PTP1C; PTPN6; SH PTP1; SHP 1; SHP 1L; SHP1

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, IHC

基因名称

PTPN6

克隆号

CGH-16

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human SHP1

计算分子量

68 kDa

实际分子量

68 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Uniprot ID

P29350

文献引用格式

PTPN6 Antibody (Clone#CGH-16) (Boster Biological Technology, Wuhan, China. Catalog#BM4236)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Tyrosine-protein phosphatase non-receptor type 6

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实验步骤

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