产品名称
Human TrkC/NTRK3 ELISA Kit
指标别名
GP145 TrkC; gp145(trkC); NT 3 growth factor receptor; NTRK3; TrkC; TrkC tyrosine kinase
交叉反应
There is no detectable cross-reactivity with other relevant proteins.
检测范围
156 pg/ml - 10000 pg/ml
基因名全称
neurotrophic receptor tyrosine kinase 3
文献引用格式
Human TrkC/NTRK3 ELISA Kit (Boster Biological Technology, Wuhan, China. Catalog#EK1676)
背景资料
Tropomyosin receptor kinase C(TrkC),also known asNT-3 growth factor receptor,neurotrophic tyrosine kinase receptor type 3, orTrkC tyrosine kinaseis aproteinthat in humans is encoded by theNTRK3gene.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
试剂盒内容
Catalog number | Description | Quantity |
---|
EK1676-CAP | 96-well plate precoated with anti- Human TRKC antibody | 1 |
EK1676-ST | Lyophilized recombinant Human TRKC standard | 10ng/tubex2 |
EK1676-DA | Biotinylated anti- Human TRKC antibody | 100ul(dilution 1:100) |
AR1103 | Avidin-Biotin-Peroxidase Complex(ABC) | 100ul(dilution 1:100) |
AR1106-1 | Sample diluent buffer | 30ml |
AR1106-2 | Antibody diluent buffer | 12ml |
AR1106-3 | ABC diluent buffer | 12ml |
AR1104 | TMB color developing agent | 10ml |
AR1105 | TMB stop solution | 10ml |
PLA-SEA | Adhesive cover | 4 |
批内差/批间差
| Intra-Assay Precision | Inter-Assay Precision |
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 16 | 16 | 16 | 24 | 24 | 24 |
Mean(pg/ml) | 330 | 1741 | 4941 | 335 | 1753 | 4967 |
Standard deviation | 18.15 | 85.3 | 390.33 | 22.78 | 92.9 | 466.89 |
CV(%) | 5.5 | 4.9 | 7.9 | 6.8 | 5.3 | 9.4 |
典型数据示例
Concentration(pg/ml) | 0 | 156 | 312 | 625 | 1250 | 2500 | 5000 | 10000 |
O.D. | 0.036 | 0.124 | 0.197 | 0.319 | 0.579 | 1.049 | 1.647 | 2.140 |
保存条件与有效期
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
样本类型
Cell Culture Supernatants, Serum and Plasma (heparin, EDTA)