Anti-CXCL1 Antibody

Rabbit polyclonal antibody

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筛选器： All WB ELISA(Cap)

A00533

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of CXCL1 using anti-CXCL1 antibody (A00533).
Lane 1: recombinant rat CXCL1 protein 10 ng.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-CXCL1 antigen affinity purified polyclonal antibody (A00533) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for CXCL1 at approximately 10 kDa.
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产品名称

Anti-CXCL1 Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

C X C motif chemokine 1; CXCL1; FSP; GRO; GRO alpha(1 73); GRO1; GROa; Growth regulated alpha protein; MGSA; MGSA a; NAP 3; SCYB1

产品类型

Polyclonal

检验物种

mouse, rat

应用范围

WB, ELISA(Cap)

基因名称

CXCL1

宿主

Rabbit

抗体亚型

IgG

免疫原

E. coli-derived rat GRO alpha recombinant protein (Position: A25-K96).

计算分子量

10 kDa

实际分子量

10 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

CXCL1(Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. It is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated.

Uniprot ID

P14095

RRID

AB_3081161

文献引用格式

CXCL1 Antibody (Boster Biological Technology, Wuhan, China. Catalog#A00533)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

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