Anti-CXCL1 Antibody

50μl/1280 100μl/2180 150μl/2800

C X C motif chemokine 1; CXCL1; FSP; GRO; GRO alpha(1 73); GRO1; GROa; Growth regulated alpha protein; MGSA; MGSA a; NAP 3; SCYB1

Polyclonal

human

IHC, ELISA

CXCL1

Rabbit

IgG

E.coli-derived human CXCL1 recombinant protein (Position: A35-N107).

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

Immunogen affinity purified.

500 ug/ml

Liquid

12 months from date of receipt，-20℃ as supplied.

CXCL1(Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROalpha, KC, Neutrophil-activating protein 3(NAP-3) and melanoma growth stimulating activity, alpha(MSGA-alpha). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation,wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated.

P09341  

CXCL1 Antibody (Boster Biological Technology, Wuhan, China. Catalog#A00533-2)

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

Boster recommends HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

C-X-C motif chemokine ligand 1

Growth-regulated alpha protein

Immunohistochemistry (IHC):	1:50-400
Enzyme linked immunosorbent assay (ELISA):	1:100-1000
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.