Anti-ABCC8 DyLight 488 Conjugated Antibody

Rabbit polyclonal antibody

说明书

筛选器： All FCM

A00895-Dyl488

100μl ￥2380
货期： 5-7天

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Figure 1. Flow Cytometry analysis of A431 cells using anti-Human SUR1 antibody (A00895-Dyl488).Overlay histogram showing A431 cells stained with A00895-Dyl488 (Blue line).anti-Human SUR1 Antibody (A00895-Dyl488,1μg/1x106 cells) for 30 min at 20°C. DyLight®488 conjugated goat anti-rabbit IgG (BA1127, 5-10μg/1x106 cells) was used as secondary antibody . Isotype control antibody (Green line) was rabbit IgG (1μg/1x106) used under the same conditions. Unlabelled sample (Red line) was also used as a control.
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产品简介>

产品名称

Anti-ABCC8 DyLight 488 Conjugated Antibody

规格/价格

100μl/2380

指标别称

SUR; HHF1; MRP8; PHHI; SUR1; ABC36; HRINS; TNDM2

产品类型

Polyclonal

检验物种

human

应用范围

FCM

基因名称

ABCC8

抗体来源

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human SUR1, which shares 97.7% amino acid (aa) sequence identity with both mouse and rat SUR1.

偶联物

DyLight 488

激发/发射光谱

Amax=488nm; Emax=515-545nm

成分

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

纯化方式

Immunogen affinity purified.

浓度

500ug/ml

产品形态

Liquid

保存条件

At -20˚C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

背景资料

ATP-binding cassette transporter sub-family C member 8 is a protein that in humans is encoded by the ABCC8 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene.

Uniprot ID

Q09428

RRID

AB_3081278

文献引用格式

ABCC8 DyLight 488 Conjugated Antibody (Boster Biological Technology, Wuhan, China. Catalog#A00895-Dyl488)

应用释义

WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC－免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法

实验方案>

实验步骤

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