Anti-NMDAR2B/GRIN2B Antibody

Rabbit polyclonal antibody

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筛选器： All WB IHC ICC/IF IP FCM ELISA

A01883-2

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of NMDAR2B/GRIN2B using anti-NMDAR2B/GRIN2B antibody (A01883-2). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat brain tissue lysates,
Lane 2: mouse brain tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-NMDAR2B/GRIN2B antigen affinity purified polyclonal antibody (A01883-2) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for NMDAR2B/GRIN2B at approximately 180 kDa. The expected band size for NMDAR2B/GRIN2B is at 166 kDa.
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产品名称

Anti-NMDAR2B/GRIN2B Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

GluN2B; GRIN2B; hNR3; NMDAR2B; NMDAR2B/GRIN2B; NR2B; NR3

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

WB, IHC, ICC/IF, IP, FCM, ELISA

基因名称

GRIN2B

宿主

Rabbit

抗体亚型

IgG

免疫原

E.coli-derived human NMDAR2B/GRIN2B recombinant protein (Position: F1132-I1480).

计算分子量

166 kDa

实际分子量

180 kDa

成分

500 ug/ml antibody with PBS，0.02% NaN3, 1 mg BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.

Uniprot ID

Q13224

文献引用格式

NMDAR2B/GRIN2B Antibody (Boster Biological Technology, Wuhan, China. Catalog#A01883-2)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

蛋白名全称

Glutamate receptor ionotropic, NMDA 2B

实验方案>

实验步骤

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