指标别称
NB1; PRV1; HNA2A; CD177; UNQ595/PRO1181; HNA-2a; NB1 GP; PRV-1
免疫原
Synthesized peptide derived from the Internal region of human CD177.
成分
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化方式
Immunogen affinity purified
保存条件
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
背景资料
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
文献引用格式
CD177 Antibody (Boster Biological Technology, Wuhan, China. Catalog#A03958)
应用释义
WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC-免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法
推荐稀释比
WB, 1:500-1:2000
IHC-P, 1:100-300