Anti-AMPK Beta 2/PRKAB2 Antibody (Clone#OTI4H4)

Mouse monoclonal antibody

筛选器： All WB

M05077-1

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期： 5-7天

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Figure 1. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PRKAB2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PRKAB2 (Cat# M05077-1)(1:2000).
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产品简介>

产品名称

Anti-AMPK Beta 2/PRKAB2 Antibody (Clone#OTI4H4)

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

AMPK beta 2; AMPK subunit beta 2; PRKAB2

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

基因名称

PRKAB2

克隆号

OTI4H4

抗体来源

Mouse

抗体亚型

IgG1

免疫原

Full length human recombinant protein of human PRKAB2 (NP_005390) produced in E.coli.

计算分子量

30 kDa

实际分子量

30.1 kDa

成分

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

纯化方式

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

浓度

500 ug/ml

产品形态

Liquid

保存条件

Stable for 12 months from date of receipt. Store at -20°C as received.

背景资料

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]

Uniprot ID

O43741

文献引用格式

AMPK Beta 2/PRKAB2 Antibody (Clone#OTI4H4) (Boster Biological Technology, Wuhan, China. Catalog#M05077-1)

应用释义

WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC－免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法

基因名全称

protein kinase, AMP-activated, beta 2 non-catalytic subunit

蛋白名全称

5'-AMP-activated protein kinase subunit beta-2

实验方案>

实验步骤

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