Anti-CD11B/Integrin Alpha M/ITGAM Antibody

Rabbit polyclonal antibody

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筛选器： All WB

BA0590-2

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Figure 1. Western blot analysis of Anti-ITGAM antibody (BA0590-2). The sample well of each lane was loaded with 50ug of sample under reducing conditions.Lane 1: JURKAT whole cell lysates,Lane 2: RAJI whole cell lysates,Use rabbit Anti-ITGAM 1:1000, probed with a goat Anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for ITGAM at approximately 170KD. The expected band size for ITGAM is at 127KD.
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产品名称

Anti-CD11B/Integrin Alpha M/ITGAM Antibody

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

CD11B; CR 3 alpha chain; CR3A; Integrin alpha M; ITGAM; MAC 1; MAC1A; MO1A; Neutrophil adherence receptor; SLEB6

产品类型

Polyclonal

检验物种

human

应用范围

基因名称

ITGAM

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human CD11b, different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.

计算分子量

127 kDa

实际分子量

170 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

ITGAM(Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT(MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2(alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3(CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated(LFA) antigen type 1(ITGAL), and p150, 95(ITGAX). By in situ hybridization, Corbi et al.(1988) demonstrated that the genes encoding the alpha subunits of LFA1(ITGAL), Mac1, and p150, 95(ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al.(1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al.(2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury(i.e., percutaneous transluminal coronary angioplasty, or PTCA).

Uniprot ID

P11215

文献引用格式

CD11B/Integrin Alpha M/ITGAM Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA0590-2)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

integrin, alpha M(complement component 3 receptor 3 subunit)

蛋白名全称

Integrin alpha-M

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实验步骤

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