Anti-P glycoprotein/ABCB1 Antibody

Rabbit polyclonal antibody

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筛选器： All IHC

BA1351-1

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Figure 1.IHC analysis using anti- ABCB1 antibody (BA1351-1). detected in paraffin-embedded section of human breast cancer tissue. Biotinylated goat anti-rabbit IgG was used as secondary antibody. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) (Catalog # SA1022) with DAB as the chromogen.
all(1)

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产品简介>

产品名称

Anti-P glycoprotein/ABCB1 Antibody

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

ABC20; ABCB1; CD243; CLCS; GP170; MDR1; Multidrug resistance protein 1; P glycoprotein; P glycoprotein 1; P-gp

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

IHC

基因名称

ABCB1

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human P Glycoprotein, different from the related rat sequence by twelve amino acids.

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier.

Uniprot ID

P08183

文献引用格式

P glycoprotein/ABCB1 Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA1351-1)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

Immunohistochemistry (IHC):	1:50-400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

Anti-P glycoprotein/ABCB1 Antibody

筛选器： All IHC

BA1351-1

产品简介>

产品名称

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基因名称

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保存条件

背景资料

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文献引用格式

应用释义

推荐配套的二抗和检测试剂

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Anti-P glycoprotein/ABCB1 Antibody

筛选器： All IHC

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