Anti-GRP78/BIP/HSPA5 Antibody

Rabbit polyclonal antibody

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筛选器： All WB IHC ICC/IF

BA2042

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Lane 1: Rat Testis Tissue LysateLane 2: A549 Cell LysateLane 3: MCF-7 Cell LysateLane 4: HELA Cell Lysate
all(6)
IHC(P): Rat Intestine Tissue
all(6)
IHC(P): Rat Cerebellum Tissue
all(6)
IHC(P): Human Lung Cancer Tissue
all(6)
ICC: HELA Cell
all(6)
IHC(F): Rat Intestine Tissue
all(6)

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产品简介>

产品名称

Anti-GRP78/BIP/HSPA5 Antibody

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

BIP; GRP 78; GRP78; GRP78/BIP; HSP A5; HSPA5; MIF2

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

WB,IHC,ICC/IF

基因名称

HSPA5

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human GRP78 BiP, identical to the related mouse and rat sequences.

计算分子量

72 kDa

实际分子量

78 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

HSPA5(heat shock 70kDa protein 5) also known as glucose-regulated protein, 78kD(GRP78) or BiP, is a member of the heat-shock protein-70(HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum. BiP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. The HSPA5 gene is mapped on 9q33.3. Shen et al.(2002)°Concluded that HSPA5 retains ATF6 in the ER by inhibiting its Golgi localization signals and that dissociation of HSPA5 during ER stress allows ATF6 to be transported to the Golgi. The findings of Shen et al.(2002) demonstrated that HSPA5 is a key element in sensing the folding capacity within the ER.

Uniprot ID

P11021

文献引用格式

GRP78/BIP/HSPA5 Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA2042)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

heat shock 70kDa protein 5(glucose-regulated protein, 78kDa)

蛋白名全称

78 kDa glucose-regulated protein

实验方案>

实验步骤

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