Anti-IDO1 Antibody

Rabbit polyclonal antibody

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筛选器： All WB

BA3659-2

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Figure 1. Western blot analysis of Anti-IDO1 antibody (BA3659-2). The sample well of each lane was loaded with 50ug of sample under reducing conditions.Lane 1: SMMC whole cell lysates,Lane 2: A549 whole cell lysates,Lane 3: Human placenta tissue lysate,Lane 4: SW620 whole cell lysates,Lane 5: U87 whole cell lysates,Lane 6: 293T whole cell lysates,Lane 7: A431 whole cell lysates,Lane 8: HELA whole cell lysates,Lane 9: COLO320 whole cell lysates,Use rabbit Anti-IDO1 1:1000, probed with a goat Anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for IDO1 at approximately 45KD. The expected band size for IDO1 is at 45KD.
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产品简介>

产品名称

Anti-IDO1 Antibody

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

CD107B; IDO; IDO 1; IDO1; INDO; indoleamine 2; 3 dioxygenase 1; Indoleamine 2; 3-dioxygenase 1; Indoleamine-pyrrole 2; 3-dioxygenase

产品类型

Polyclonal

检验物种

human

应用范围

基因名称

IDO1

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human IDO1.

计算分子量

45 kDa

实际分子量

45 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

IDO1(INDOLEAMINE 2,3-DIOXYGENASE), INDO or IDO, is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells. This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine. By fluorescence in situ hybridization, the assignment is narrowed to chromosome 8p12-p11. INDO Interferon-gamma has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase. During inflammation, IDO is upregulated in dendritic cells and phagocytes by proinflammatory stimuli, most notably IFNG, and the enzyme then uses superoxide as a 'cofactor' for oxidative cleavage of the indole ring of tryptophan, yielding an intermediate that deformylates to L-kynurenine.

Uniprot ID

P14902

文献引用格式

IDO1 Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA3659-2)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

indoleamine 2,3-dioxygenase 1

蛋白名全称

Indoleamine 2,3-dioxygenase 1(IDO-1)

实验方案>

实验步骤

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