产品名称
Anti-IL12B Antibody (Clone#OTI1A3)
规格/价格
50μl/1180 100μl/1960 150μl/2780
指标别称
CLMF; CLMF p40; CLMF2; IL 12 subunit p40; IL 12B; IL12B; IL-12B; Interleukin 12 subunit beta; NKSF; NKSF2
免疫原
Full length human recombinant protein of human IL12B (NP_002178) produced in SF9 cell.
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
文献引用格式
IL12B Antibody (Clone#OTI1A3) (Boster Biological Technology, Wuhan, China. Catalog#M01152)
应用释义
WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC-免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法
基因名全称
Interleukin-12 subunit beta|IL-12B|Cytotoxic lymphocyte maturation factor 40 kDa subunit|CLMF p40|IL-12 subunit p40|NK cell stimulatory factor chain 2|NKSF2