Anti-Lamin A/C Antibody

Rabbit Monoclonal Antibody

说明书

筛选器： All WB IHC ICC/IF IP FCM

BM4105

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Western blot analysis of Lamin A/C expression in HeLa whole cell lysates.
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Immunohistochemical analysis of paraffin-embedded human kidney, using Lamin A/C Antibody.
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Immunofluorescent analysis using the Antibody.
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All lanes use the Antibody for 1 hour at room temperature.
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产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-Lamin A/C Antibody

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; HGPS; IDC; lamin A; lamin A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; Prelamin A/C; PRO1; progerin

产品类型

Monoclonal

检验物种

human

应用范围

WB, IHC, ICC/IF, IP, FCM

基因名称

LMNA

抗体来源

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human Lamin A/C

计算分子量

74 kDa

实际分子量

70-74 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

Lamins are structural protein components of the nuclear lamina, a protein network underlying the inner nuclear membrane that determines nuclear shape and size. There are three types of lamins, A,B and C. The lamin A/C (LMNA) gene contains 12 exons. Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and lamin C. Lamin A/C is mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy, and Hutchinson-Gilford progeria syndrome. Lamin A/C deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription.

Uniprot ID

P02545

文献引用格式

Lamin A/C Antibody (Boster Biological Technology, Wuhan, China. Catalog#BM4105)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Prelamin-A/C

实验方案>

实验步骤

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